O-Acetylpsilocin (also known as psilacetin, 4-acetoxy-DMT, 4-AcO-DMT, or synthetic shrooms) is a semi-synthetic psychoactive drug that has been suggested by David Nichols to be a potentially useful alternative to psilocybin for pharmacological studies, as they are both believed to be prodrugs of psilocin.[2][3] However, some users report that O-acetylpsilocin’s subjective effects differ from those of psilocybin and psilocin.[4][5] Additionally, some users prefer 4-AcO-DMT to natural psilocybin mushrooms due to feeling fewer adverse side effects such as nausea and heavy body load, which are more frequently reported in experiences involving natural mushrooms.[6] It is the acetylated form of the psilocybin mushroomalkaloidpsilocin and is a lower homolog of 4-AcO-MET, 4-AcO-DET, 4-AcO-MiPT and 4-AcO-DiPT.
4-AcO-DMT, also called O-acetylpsilocin, psilacetin, and psilocetin, is a synthetic psychedelic substance. The compound is structurally similar to magic mushrooms’ primary hallucinogenic compound, psilocybin. Like psilocybin, 4-AcO-DMT acts as a prodrug to psilocin, which means that the body converts the compound into psilocin after ingestion. This function is incredibly valuable as psilocin is the active tryptamine that exerts magic mushrooms’ psychedelic effects upon ingestion.
Explorers often report enhanced colors, geometric patterns, and visual distortions or hallucinations. These can range from subtle enhancements in color and texture to complex, shifting patterns and fractal-like images.
Sounds may seem more distinct or take on a different quality, such as echoing. Music can feel more emotionally profound.
Some people experience a heightened sense of touch, often described as more immersive.
Emotional Shifts
4-AcO-DMT can induce a wide range of emotional states, from euphoria and bliss to introspection and empathy. In some cases, it can also lead to challenging experiences, such as anxiety or introspective thoughts. There’s often an increased feeling of openness and connectedness with others, similar to MDMA but less intense.
Cognitive Alterations
Users often report changes in their patterns, including nonlinear thinking, a sense of interconnectedness, or profound philosophical insights. Time may slow down, speed up, or become irrelevant.
Comparing 4-AcO-DMT with Psilocybin
4-AcO-DMT’s effects are largely similar to psilocybin due to their shared metabolic pathway to psilocin.
However, some people report subtle differences.
The onset and duration of effects can differ slightly depending on the route of administration and individual metabolism. Some people report that 4-AcO-DMT has a smoother onset than psilocybin, potentially leading to a more gentle experience. The emotional and cognitive effects can be very subjective and variable between individuals, but both substances are known for their potential to induce profound and meaningful experiences.
Oral Ingestion: Most people ingest 4-AcO-DMT through it as pills, capsules, or powders dissolved in liquid. The onset of effects typically takes 20-40 minutes, with the experience peaking around 2-3 hours and lasting up to 6 hours.
Insufflation (Snorting): Snorting 4-AcO-DMT leads to a quicker onset of effects. This method may make the experience’s overall duration shorter and more potent.
Less common methods include vaporization and intravenous administration, which may have increased risks and difficulty controlling the dosage.
What is 4-AcO-DMT?
Reviews
There are no reviews yet.